AI-Designed Gene Editing

Halting genetic diseases, one edit at a time

Neoclease designs custom nucleases with generative AI: gene editors built for one target, miniaturized to reach tissue standard editors can't.

Our vision

Redefining biology.

Finding a new nuclease used to mean searching nature for one. What if we could rewrite our genetics to eliminate the root causes of disease, rather than just treat their symptoms?

Lead Program

LRRK2, Parkinson's Disease

Our first editor targets LRRK2, with the goal of slowing or halting Parkinson's disease progression at its genetic root.

View the pipeline
Our Mission

Gene editing as the cornerstone of precision medicine.

With over 6,000 monogenic diseases in existence, we refuse to rely on a one-size-fits-all approach, instead developing tailored nucleases, each designed to combat a specific disease or gene of interest.

The Neoclease approach

Our nucleases are engineered for precision editing for one specific DNA gene, aiming to reduce side effects and open the door to real cures, not just symptom management.

Meet the team
Collaboration for Impact

We build alongside industry leaders, not alone.

Neoclease collaborates with and is supported by research institutions and industry partners to drive innovation in gene-editing technologies and therapies, because a challenge this large can't be solved solo.

Want to learn more?

Whether you're an investor, a collaborator, or simply passionate about the future of healthcare, we'd love to hear from you.